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- ▌ Statistical Analysis Usage Guide · tools-only bundleStatistical analysis identifies metabolites associated with biological conditions. Methods range from simple univariate tests to multivariate models for biomarker discovery.
- ▌ Model Interpretation Usage Guide · tools-only bundleExplain machine learning predictions on omics data using SHAP values for global and local feature attribution, and LIME for model-agnostic explanations.
- ▌ R Markdown Reports Usage Guide · tools-only bundleR Markdown combines code, results, and narrative into reproducible documents. Output to HTML, PDF, Word, or presentations.
- ▌ Cell Cell Communication Usage Guide · tools-only bundleCell-cell communication analysis identifies ligand-receptor interactions between cell types from scRNA-seq data to understand tissue organization, signaling networks, and intercellular coordination.
- ▌ Multi Omics Integration Pipeline Usage Guide · tools-only bundleThis workflow integrates multiple molecular data types (transcriptomics, proteomics, metabolomics, etc.) to discover shared biological signals and cross-modal biomarkers.
- ▌ Imputation Qc Usage Guide · tools-only bundleQuality control of imputed data is essential before downstream analysis, as poor quality imputation can introduce false positives in GWAS and bias effect estimates.
- ▌ Molecular I O Usage Guide · tools-only bundleRead, write, and convert molecular file formats including SMILES, SDF, MOL2, and PDB. Includes structure standardization pipeline for consistent molecular representations.
- ▌ Spatial Cell Cell Communication Usage Guide · tools-only bundleThis skill covers analyzing cell-cell communication in spatial transcriptomics data using ligand-receptor analysis with Squidpy. Identify which cell types are communicating and through which signaling pathways.
- ▌ Chip Seq Visualization Usage Guide · tools-only bundleCreate heatmaps, profile plots, and genome browser-style visualizations for ChIP-seq data using deepTools (CLI), ChIPseeker (R), and Gviz (R).
- ▌ Transcription And Translation Usage Guide · tools-only bundleThis skill enables AI agents to help you convert between DNA, RNA, and protein sequences using Biopython.
- ▌ Population Structure Usage Guide 2 · tools-only bundlePopulation structure analysis identifies genetic ancestry and stratification using PCA (continuous clustering) and ADMIXTURE (discrete ancestry proportions).
- ▌ Alphafold Predictions Usage Guide · tools-only bundleDownload and analyze AI-predicted protein structures from the AlphaFold database, including confidence scores (pLDDT) and predicted aligned error (PAE) for assessing prediction quality.
- ▌ Feature Selection Usage Guide · tools-only bundleSelect informative features for biomarker discovery using Boruta all-relevant selection, mRMR minimum redundancy, and LASSO regularization.
- ▌ Blast Searches Usage Guide · tools-only bundleThis skill enables AI agents to help you run BLAST searches against NCBI databases using Biopython, finding similar sequences to identify unknown genes or find homologs.
- ▌ Mixomics Analysis Usage Guide · tools-only bundlemixOmics provides multivariate methods for multi-omics integration, including both supervised (DIABLO, sPLS-DA) and unsupervised (sPLS, sPCA) approaches with sparse feature selection.
- ▌ Metabolomics Pipeline Usage Guide · tools-only bundleThis workflow processes raw mass spectrometry data through peak detection, alignment, normalization, statistical analysis, and pathway interpretation.
- ▌ Spatial Preprocessing Usage Guide · tools-only bundleThis skill covers quality control, filtering, normalization, and feature selection for spatial transcriptomics data using Squidpy and Scanpy.
- ▌ Count Matrix Ingestion Usage Guide · tools-only bundleLoad gene expression count matrices from various quantification tools (featureCounts, Salmon, kallisto, STAR, HTSeq, 10X) into pandas DataFrames for downstream analysis.
- ▌ Tree Visualization Usage Guide · tools-only bundleThis skill creates publication-quality phylogenetic tree figures using Bio.Phylo's matplotlib integration. It supports customizing labels, colors, and exporting to various image formats.
- ▌ Cnv Visualization Usage Guide · tools-only bundleEffective CNV visualization helps identify patterns, validate calls, and communicate findings. This guide covers genome-wide profiles, region-specific plots, and cohort-level comparisons.
- ▌ Pathogen Typing Usage Guide · tools-only bundleIdentify bacterial strain types using MLST, cgMLST, and SNP-based approaches for outbreak investigation and surveillance.
- ▌ Fragment Analysis Usage Guide · tools-only bundleAnalyze cfDNA fragment size distributions and fragmentomics patterns for cancer detection. Extract nucleosome positioning signals and DELFI-style fragmentation profiles.
- ▌ Methylation Based Detection Usage Guide · tools-only bundleAnalyze cfDNA methylation patterns for cancer detection and tissue-of-origin analysis. Uses bisulfite sequencing or cfMeDIP-seq for methylation profiling.
- ▌ Reactome Pathway Enrichment Usage Guide · tools-only bundleReactomePA provides pathway enrichment analysis using the Reactome database, a curated peer-reviewed knowledgebase of biological pathways with deep hierarchy and reaction-level detail.
- ▌ Cnvkit Analysis Usage Guide 2 · tools-only bundleCNVkit is the standard tool for detecting copy number variants from targeted sequencing (exome, gene panels). It uses both on-target and off-target reads to infer copy number across the genome.
- ▌ Gene Id Mapping Usage Guide · tools-only bundleConvert between different gene identifier systems (Ensembl, Symbol, Entrez, UniProt) using mygene, biomaRt, and org.db packages for cross-database integration.
- ▌ Complete MCP Setup Guide MCP 2025 · tools-only bundleStep-by-step guide to set up the Skill Seeker MCP server with 5 supported AI coding agents.
- ▌ Technology Evaluation Metrics · tools-only bundleDetailed metrics and calculations used in technology stack evaluation.
- ▌ MCP Server Configuration Guide · tools-only bundleHow to configure Aleph as an MCP server in all major MCP-compatible clients: Cursor, VS Code, Claude Desktop, Codex CLI, Windsurf, Kimi CLI, and others.
- ▌ Complete MCP Setup Guide MCP 2025 2 · tools-only bundleStep-by-step guide to set up the Skill Seeker MCP server with 5 supported AI coding agents.
- ▌ MCP Server Configuration Guide 2 · tools-only bundleThis guide explains how to properly configure aleph as an MCP server in all major MCP-compatible clients: Cursor, VS Code, Claude Desktop, OpenAI Codex, Windsurf, and others.
- ▌ AI Tool Protocol Scan · tools-only bundleA.I.G leverages AI agents for comprehensive MCP Server and Skills security assessment, supporting both source code audits and remote URL scanning.
- ▌ Database Archival System · tools-only bundleImplement production-ready data archival strategies for PostgreSQL and MySQL that move historical records to archive tables or cold storage (S3, Azure Blob, GCS) with automated retention policies, compression…
- ▌ Structure I O Usage Guide · tools-only bundleThis skill handles reading, writing, and downloading protein structure files. It supports PDB, mmCIF, MMTF, and BinaryCIF formats, with tools for downloading structures from RCSB PDB and extracting metadata.
- ▌ Agentkits Marketing Usage Guide · tools-only bundleComplete guide to using agentkits-marketing for production marketing workflows.
- ▌ Project Structure Reference · tools-only bundleThe Definitions object is the entry point for all Dagster objects.
- ▌ Go Project Structure · tools-only bundleBest for small applications, CLIs, microservices with fewer than ~10 handlers, and projects where a single developer or small team owns the entire codebase.
- ▌ Project Structure Reference 2 · tools-only bundleThe Definitions object is the entry point for all Dagster objects.
- ▌ Structure Analysis Summary · tools-only bundleThe Structure Agent has completed a comprehensive depth 0 analysis of the TunaCode source code directory at /src/.
- ▌ Mermaid Hover Tooltip Fix · tools-only bundleWhen testing the Mermaid workflow diagram at http://localhost:8000/microsims/sims/basic/#workflow-example-microsim-creation, the hover tooltips were not appearing.
- ▌ MCP Prefix Issue In Claude Code · tools-only bundleThe skills-lister MCP server is correctly implemented and configured, but Claude Code is not exposing the MCP tools with the required mcp__ prefix.
- ▌ Mental Models Reference · tools-only bundleConceptual models that sharpen reasoning across all modes. Apply before analysis to frame the problem correctly.
- ▌ No More Context Bloat With MCP Manager Subagent Plus MCP · tools-only bundleWhen I finished reading Anthropic’s “Code execution with MCP” article, a sudden idea flashed in my mind
- ▌ Gas Fee Optimizer · tools-only bundleYou are a gas fee optimization specialist. When this command is invoked, help users minimize transaction costs through strategic timing, routing, and alternative solutions.
- ▌ Database Partition Manager · tools-only bundleDesign, implement, and manage table partitioning strategies for massive datasets with automated partition maintenance, query optimization, and data lifecycle management.
- ▌ MCP Integration 3 · tools-only bundleModel Context Protocol (MCP) integration for connecting Claude Code to external tools and services.
- ▌ Migration Guide Connected App External Client App 2 · tools-only bundleStep-by-step guide for migrating from Connected Apps to External Client Apps (ECAs).
- ▌ The Cornerstone Lbyl Over Eafp · tools-only bundleThis is the single most important rule in dignified Python. Every pattern below flows from this principle.
- ▌ Senhasegura MCP Tools Integration · tools-only bundleGuide for integrating senhasegura with Claude Code using MCP (Model Context Protocol) tools.
- ▌ MCP Integration 4 · tools-only bundleOpenAkita supports the Model Context Protocol (MCP) for connecting to external services.
- ▌ MCP Integration 5 · tools-only bundleModel Context Protocol (MCP) enables AI assistants like Claude to interact with external tools and data sources. This guide covers setting up the Airbyte Agent MCP server for use with Claude Code and Claude Desktop.
- ▌ MCP Integration 6 · tools-only bundleModel Context Protocol (MCP) enables AI assistants like Claude to interact with external tools and data sources. This guide covers setting up the Airbyte Agent MCP server for use with Claude Code and Claude Desktop.
- ▌ Migration Guide To Shadcn UI · tools-only bundleThis guide helps you migrate from other UI libraries to shadcn/ui.
- ▌ Mermaid Quick Reference 2 · tools-only bundleQuick reference guide for Mermaid diagram syntax used in sf-diagram.
- ▌ Conversation Turn Flow · tools-only bundleThis document maps how a conversation turn flows through the system from user input to agent response to UI display.
- ▌ Conversation Turn Flow 2 · tools-only bundleThis document maps how a conversation turn flows through the system from user input to agent response to UI display.
- ▌ MCP Server Integration · tools-only bundleThis guide explains how to benchmark your MCP (Model Context Protocol) server with mcpbr.
- ▌ MCP Server Integration 2 · tools-only bundleMCP (Model Context Protocol) servers allow you to extend Claude's capabilities with custom tools and functions.
- ▌ Migration Guide Environment Variable Updates · tools-only bundleStarting with version 2.2.0, all environment variables have been renamed from VOICEMODE prefix to VOICEMODE_ prefix to reflect the project's new name.
- ▌ Pyhealth Medical Code Translation · tools-only bundleHealthcare data uses multiple coding systems and standards. PyHealth's MedCode module enables translation and mapping between medical coding systems through ontology lookups and cross-system mappings.
- ▌ Skill Scaffold 52 · tools-only bundleThis skill optimizes Exa costs: understanding pricing model (requests, content extraction), minimizing numResults to actual needs, selective content extraction (text vs highlights vs full), caching to reduce duplicate…
- ▌ Messaging API V2 Guide Miaw 2 · tools-only bundleThis guide covers building custom clients for Messaging for In-App and Web (MIAW), enabling Agentforce and Service Cloud conversations outside of Salesforce.
- ▌ Agent Response Panel · tools-only bundleAgent text responses are rendered in styled panels matching the NeXTSTEP tool panel aesthetic. This provides visual consistency across all output types.
- ▌ SQL Query Builder 3 · tools-only bundleGenerates optimized SQL queries from natural language descriptions, supporting SELECT, INSERT, UPDATE, DELETE with JOINs, indexes, and best practices.
- ▌ Pydantic Removal Contract · tools-only bundleThis document defines the minimal internal contracts that must remain stable while replacing pydantic-ai: request loop responsibilities, canonical message shapes, tool lifecycle handling, persistence format, and…
- ▌ Meeting Structures For Developers · tools-only bundleTemplates and structures for common software development meetings. Use these to run effective meetings and ensure productive outcomes.
- ▌ Microsim Add Icons 2 · tools-only bundleThe microsim-add-icons skill adds clickable Creative Commons license and fullscreen navigation icons to the control region of an existing p5.js MicroSim.
- ▌ Class To Modern React Migration Guide · tools-only bundleModern Next.js 13+ supports Server Components, which cannot use hooks.
- ▌ Skill Scaffold 56 · tools-only bundleThis skill implements robust rate limit handling for FireCrawl API operations. It covers reading and respecting rate limit headers, implementing exponential backoff with jitter to avoid thundering herd problems, request…
- ▌ Microsim Standardization Skill 2 · tools-only bundleThe microsim-standardization skill performs comprehensive audits and quality upgrades of MicroSim directories to ensure they meet documentation and structural standards.
- ▌ Skill Scaffold 55 · tools-only bundleThis skill implements full website crawling with FireCrawl's crawl endpoint. It covers crawl configuration including max depth, URL include/exclude patterns, sitemap utilization, rate limiting, and page limits.
- ▌ Express To Nestjs Migration Guide · tools-only bundleGradually replace Express routes with NestJS while both run simultaneously.
- ▌ Skill Scaffold 53 · tools-only bundleThis skill optimizes Exa performance: implementing query result caching (Redis, in-memory), cache key strategies for search queries, optimal numResults configuration, content extraction option optimization, parallel…
- ▌ Research Pydantic AI To Alchemy Rs Migration · tools-only bundleMap out what needs to change to migrate from pydantic-ai to alchemy-rs for LLM API calls, while keeping Python for state management and agent loop.
- ▌ File Scaffold 119 · tools-only bundleThis skill provides production-ready patterns for Clay enrichment operations. It covers singleton API client initialization, robust error handling with structured logging, batch processing for multiple records…
- ▌ Medical Journal Structured Abstract Examples · tools-only bundleExamples of structured abstracts for NEJM, Lancet, JAMA, and BMJ showing the labeled section format expected at medical journals.
- ▌ Skill Scaffold 54 · tools-only bundleThis skill implements efficient batch processing for large URL lists with FireCrawl.
- ▌ Research Recent Major Changes Last 3 Days · tools-only bundleDocument all major changes from the last 3 days of development (Jan 25-28, 2026), including merged PRs, architectural refactors, and new features.
- ▌ Coordinated Agents 7 · tools-only bundleYou are the Research Orchestrator - coordinating swarm-style parallel information gathering.
- ▌ Pre Flight Checks · tools-only bundlestartstream() clears _insertionanchor = None to prevent stale positioning. clear() also clears the anchor.
- ▌ Research Streaming Response And Panel Display In Tunacode · tools-only bundleExplain how streaming responses work in the TunaCode TUI and what panels are shown before the final answer. This includes understanding the dual-display architecture (streaming overlay vs.
- ▌ Research Insertbeforestream Tool Panel Investigation · tools-only bundleInvestigate the insertbeforestream() implementation to understand why tool panels might not be appearing correctly during streaming, despite the reported fix.
- ▌ Research Tools Layer Cross Layer Import Analysis · tools-only bundleFull audit of tools layer imports from configuration, exceptions, constants, and types. Map which files, what logic, and why.
- ▌ Medical Terminology And Coding Standards 2 · tools-only bundleThis reference provides comprehensive medical terminology, coding systems, abbreviations, and nomenclature standards. Use these guidelines to ensure accurate, standardized clinical documentation.
- ▌ Directory Structure 18 · tools-only bundleThis skill provides advanced troubleshooting techniques for complex Ideogram issues. It covers deep API debugging, network analysis, response quality assessment, intermittent failure diagnosis, and edge case handling.
- ▌ Lsp Module · tools-only bundleImplements a minimal Language Server Protocol client to fetch diagnostic feedback (errors, warnings) from language servers.
- ▌ Lsp Configuration Reference · tools-only bundleComplete guide for configuring Language Server Protocol in this Neovim setup.
- ▌ Type Annotation · tools-only bundleIn Swift, there are two kinds of types: named types and compound types. A named type is a type that can be given a particular name when it's defined. Named types include classes, structures, enumerations, and protocols.
- ▌ Algorand Python Types · tools-only bundleAlgorand Python provides statically-typed representations of AVM (Algorand Virtual Machine) types. These types differ from standard Python types and are essential for writing correct smart contracts.
- ▌ LLM Configuration · tools-only bundleConfigure LLM for semantic extraction (L0/L1 generation) and reranking.
- ▌ Supported Models · tools-only bundleIntentKit supports a wide range of LLM providers and models to give you flexibility in choosing the right model for your needs.
- ▌ LLM Inference · tools-only bundleLLM selects the best UI component to visualize that data, and also configures it by selecting which values from the data have to be shown.
- ▌ MCP Reference · tools-only bundleThe Atlassian MCP does not currently support creating issue links. Use the bundled jira-link-issues script instead.
- ▌ Types Module · tools-only bundleCentralizes all type aliases, protocols, and dataclass definitions for type safety and consistency across the codebase.
- ▌ Constants Module · tools-only bundleCentralizes global constants, magic strings, UI text, error messages, and application-wide fixed values.
- ▌ LLM Integration Guide For Intentkit · tools-only bundleThis guide provides comprehensive information for Large Language Models (LLMs) working with the IntentKit autonomous agent framework.
- ▌ MCP Overview · tools-only bundleimport Tabs from '@theme/Tabs'; import TabItem from '@theme/TabItem'; import Image from '@theme/IdealImage';
- ▌ MCP Overview 2 · tools-only bundleimport Tabs from '@theme/Tabs'; import TabItem from '@theme/TabItem'; import Image from '@theme/IdealImage';
- ▌ MCP Overview 3 · tools-only bundleimport Tabs from '@theme/Tabs'; import TabItem from '@theme/TabItem'; import Image from '@theme/IdealImage';
- ▌ MCP Model Context Protocol · tools-only bundleMCP is an open standard for connecting AI models to external services. Skill Compose uses MCP to extend agent capabilities beyond built-in tools — adding web search, Git operations, URL fetching, and more.