Coding & Dev Tools

Use when annotating VCF files with flanking sequence information (INFO/FS tag) or masking regions/variants in flanking sequences.

Use when converting FASTA sequence records into XML for downstream EDirect or XML-based sequence processing.

Use when converting GenBank format files to table format as part of the Entrez Direct toolkit from bioconda.

Use when converting GenBank flatfiles into XML for downstream EDirect or XML-based sequence annotation workflows.

Use when a GFF file needs bcftools/csq-compatible gene and transcript attributes before consequence annotation.

Use when sampling synthetic sequences, alignments, or consensus sequences from one or more profile HMMs.

Use when running HMMER master or worker daemon services that front `phmmer`, `hmmsearch`, and `hmmscan` against cached databases.

Use when you need to identify, view, or copy HTS-format files (BAM, CRAM, VCF, BCF). Use for inspecting file headers or viewing textual representations of binary HTS files.

Use when converting INI-style configuration files into XML for downstream EDirect or XML-based processing.

Use when inferring maximum-likelihood phylogenetic trees, selecting substitution models, running bootstrap support analyses, or performing partitioned phylogenetic analyses on sequence alignments.

Use when profiling nucleotide content (AT/GC percentages, base counts) of genomic intervals against a FASTA reference.

Use when predicting RNA secondary structures, calculating minimum free energy (MFE) folds, or computing partition functions and base pairing probabilities for RNA sequences.

Use when computing RNA specific heat profiles from sequence data to analyze melting behavior and thermal stability across temperature ranges.

Use when performing pairwise structural alignments of RNA sequences that incorporate both sequence and structure information through base pair propensity vectors.

Use when converting SCN-format records into XML for downstream EDirect or XML-based processing.

Use when you need to annotate BAM alignments with a two-character tag based on overlaps with BED, GFF, or VCF annotation files, such as labeling reads by feature class or interval source.

Use when converting tabular text into XML for downstream EDirect or XML-based processing.

Use when searching protein query sequences against a translated nucleotide database to identify protein-coding regions or homologs in genomic data.

Use when converting NCBI XML sequence records to FASTA format, typically after fetching data with efetch from the Entrez Direct toolkit.

Use when extracting INSDSeq XML feature tables into tab-delimited text for downstream parsing or annotation review.

Use when performing multiple sequence alignments on protein or nucleotide sequences, generating phylogenetic trees, or producing alignment output in various formats.

Use when you need to remove adapter sequences from high-throughput sequencing reads, trim low-quality bases, or filter reads by length. Supports single-end and paired-end FASTQ/FASTA input with error-tolerant adapter matching.

Expert GDPR compliance assistant covering all four core workflows: (1) auditing code and systems for GDPR violations, (2) drafting GDPR-compliant documents such as privacy policies, Data Processing Agreements (DPAs), and consent notices, (3) answering GDPR compliance questions with authoritative article citations, and (4) reviewing data flows and PII handling practices. Use this skill whenever the user mentions GDPR, data protection, privacy compliance, lawful basis, data subject rights, DPA, privacy notices, consent management, data breaches, DPIAs, controller/ processor relationships, cross-border data transfers, or any EU/UK data privacy topic. Also trigger for questions like "is this GDPR compliant?", "how do I handle personal data?", "what does a privacy policy need?", or any request involving PII, personal data, or data retention in a regulatory context.

Expert NIST Cybersecurity Framework (CSF) advisor covering CSF 2.0 and CSF 1.1. Use this skill whenever a user asks about NIST CSF, cybersecurity risk management, the six CSF functions (Govern, Identify, Protect, Detect, Respond, Recover), CSF profiles, implementation tiers, gap assessments, organizational profiles, community profiles, CSF core subcategories, informative references, or mapping to other frameworks (NIST SP 800-53, ISO 27001, CIS Controls, COBIT). Also trigger for questions like "how do I implement NIST CSF?", "what does CSF 2.0 change?", "help me build a CSF profile", "how do I assess my cybersecurity posture?", or any request involving organizational cybersecurity risk strategy or framework alignment.

Centralized 'Truth Engine' for cross-jurisdictional legal context (US, EU, CA) and contract scaffolding.

Unified Diary System: A context-preserving automated logger for multi-project development.

Convert human-written CLAUDE.md into AI-native structured-label format. Battle-tested across 4 models. Same rules, fewer tokens, higher compliance.

Build ultra-fast web APIs and full-stack apps with Hono — runs on Cloudflare Workers, Deno, Bun, Node.js, and any WinterCG-compatible runtime.

Write idiomatic C++ code with modern features, RAII, smart pointers, and STL algorithms. Handles templates, move semantics, and performance optimization.

Cirq is Google Quantum AI's open-source framework for designing, simulating, and running quantum circuits on quantum computers and simulators.

Write idiomatic Ruby code with metaprogramming, Rails patterns, and performance optimization. Specializes in Ruby on Rails, gem development, and testing frameworks.

Video and audio perception, indexing, and editing. Ingest files/URLs/live streams, build visual/spoken indexes, search with timestamps, edit timelines, add overlays/subtitles, generate media, and create real-time alerts.

SymPy is a Python library for symbolic mathematics that enables exact computation using mathematical symbols rather than numerical approximations.

Scaffold a new mobile-first page using StyleSeed Toss layout patterns, section rhythm, and existing shell components.

Scanpy is a scalable Python toolkit for analyzing single-cell RNA-seq data, built on AnnData. Apply this skill for complete single-cell workflows including quality control, normalization, dimensionality reduction, clustering, marker gene identific...

Post-process AI-generated text through the unslop CLI to strip AI writing patterns before publishing