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1. ▌
   Bio Machine Learning Biomarker Discovery 2 · tools-only bundle

   Selects informative features for biomarker discovery using Boruta all-relevant selection, mRMR minimum redundancy, and LASSO regularization. Use when identifying biomarkers from high-dimensional omics data.
   7 repo stars
2. ▌
   Bio Genome Annotation Eukaryotic Gene Prediction 2 · tools-only bundle

   Predict protein-coding genes in eukaryotic genomes using BRAKER3 for combined RNA-seq and protein evidence, or GALBA for protein-only evidence. Runs Augustus with trained parameters for accurate gene models. Use when annotating a newly assembled eukaryotic genome or improving existing gene predictions.
   7 repo stars
3. ▌
   Bio Differential Splicing 2 · tools-only bundle

   Detects differential alternative splicing between conditions using rMATS-turbo (BAM-based) or SUPPA2 diffSplice (TPM-based). Reports events with FDR-corrected significance and delta PSI effect sizes. Use when comparing splicing patterns between treatment groups, tissues, or disease states.
   7 repo stars
4. ▌
   Bio Sashimi Plots 2 · tools-only bundle

   Creates sashimi plots showing RNA-seq read coverage and splice junction counts using ggsashimi or rmats2sashimiplot. Visualizes differential splicing events with grouped samples and junction read support. Use when visualizing specific splicing events or validating differential splicing results.
   7 repo stars
5. ▌
   Bio Rna Structure Secondary Structure Prediction 2 · tools-only bundle

   Predicts RNA secondary structures using minimum free energy folding and partition function analysis with ViennaRNA (RNAfold, RNAalifold, RNAcofold). Computes base-pair probabilities, centroid structures, and consensus structures from alignments. Use when predicting RNA folding, evaluating structural stability, or comparing structures across homologs.
   7 repo stars
6. ▌
   Bio Longread Qc 2 · tools-only bundle

   Quality control for long-read sequencing data using NanoPlot, NanoStat, and chopper. Generate QC reports, filter reads by length and quality, and visualize read characteristics. Use when assessing ONT or PacBio run quality or filtering reads before assembly or alignment.
   7 repo stars
7. ▌
   Bio Genome Intervals Gtf Gff Handling 2 · tools-only bundle

   Parse, query, and convert GTF and GFF3 annotation files. Extract gene, transcript, and exon coordinates using gffread, gtfparse, and gffutils. Use when extracting specific features from gene annotations or converting between annotation formats.
   7 repo stars
8. ▌
   Bio Metabolomics Pathway Mapping 2 · tools-only bundle

   Map metabolites to biological pathways using KEGG, Reactome, and MetaboAnalyst. Perform pathway enrichment and topology analysis. Use when interpreting metabolomics results in the context of biochemical pathways.
   7 repo stars
9. ▌
   Bio Pdb Geometric Analysis 2 · tools-only bundle

   Perform geometric calculations on protein structures using Biopython Bio.PDB. Use when measuring distances, angles, and dihedrals, superimposing structures, calculating RMSD, or computing solvent accessible surface area (SASA).
   7 repo stars
10. ▌
    Bio Proteomics Dia Analysis 2 · tools-only bundle

    Data-independent acquisition (DIA) proteomics analysis with DIA-NN and other tools. Use when analyzing DIA mass spectrometry data with library-free or library-based workflows for deep proteome profiling.
    7 repo stars
11. ▌
    Bio Epitranscriptomics Modification Visualization 2 · tools-only bundle

    Create metagene plots and browser tracks for RNA modification data. Use when visualizing m6A distribution patterns around genomic features like stop codons.
    7 repo stars
12. ▌
    Chapter Content Generator 5 · tools-only bundle

    This skill generates comprehensive chapter content for intelligent textbooks after the book-chapter-generator skill has created the chapter structure. Use this skill when a chapter index.md file exists with title, summary, and concept list, and detailed educational content needs to be generated at the appropriate reading level with rich non-text elements including diagrams, infographics, and MicroSims. (project, gitignored)
    7 repo stars
13. ▌
    Bio De Results 2 · tools-only bundle

    Extract, filter, annotate, and export differential expression results from DESeq2 or edgeR. Use for identifying significant genes, applying multiple testing corrections, adding gene annotations, and preparing results for downstream analysis. Use when filtering and exporting DE analysis results.
    7 repo stars
14. ▌
    Plugin Creator 3 · tools-only bundle

    Orchestrates specialized agents to create high-quality Claude Code plugins. Delegates to plugin-assessor agent for domain research and code discovery, general-purpose agents for official docs verification, validation scripts for schema checks, and review agents for quality assessment. Use when creating new plugins or improving existing ones.
    7 repo stars
15. ▌
    Bio De Deseq2 Basics 2 · tools-only bundle

    Perform differential expression analysis using DESeq2 in R/Bioconductor. Use for analyzing RNA-seq count data, creating DESeqDataSet objects, running the DESeq workflow, and extracting results with log fold change shrinkage. Use when performing DE analysis with DESeq2.
    7 repo stars
16. ▌
    Bio Chipseq Differential Binding 2 · tools-only bundle

    Differential binding analysis using DiffBind. Compare ChIP-seq peaks between conditions with statistical rigor. Requires replicate samples. Outputs differentially bound regions with fold changes and p-values. Use when comparing ChIP-seq binding between conditions.
    7 repo stars
17. ▌
    Yandex Wordstat 2 · tools-only bundle

    Анализ поискового спроса через Yandex Wordstat API. Используй когда нужно: исследовать спрос, семантическое ядро, частотность запросов, сезонность или региональный спрос. Топ до 2000 запросов, ассоциации, динамика, экспорт CSV.
    7 repo stars
18. ▌
    Bio Epidemiological Genomics Transmission Inference 2 · tools-only bundle

    Infer pathogen transmission networks and identify likely transmission pairs using TransPhylo and outbreak reconstruction algorithms. Estimate who-infected-whom from genomic and epidemiological data. Use when investigating outbreak transmission chains or identifying superspreaders.
    7 repo stars
19. ▌
    Power Query Coaching 2 · tools-only bundle

    Coaches users to transform messy data into clean, analysis-ready formats using Power Query UI. Diagnoses data problems, visualizes goals, and guides step-by-step transformations.
    7 repo stars
20. ▌
    Sf Apex 3 · tools-only bundle

    Generates and reviews Salesforce Apex code with 2025 best practices and 150-point scoring. Use when writing Apex classes, triggers, test classes, batch jobs, or reviewing existing Apex code for bulkification, security, and SOLID principles.
    7 repo stars
21. ▌
    Phoenix Code Review 2 · tools-only bundle

    Reviews Phoenix code for controller patterns, context boundaries, routing, and plugs. Use when reviewing Phoenix apps, checking controllers, routers, or context modules.
    7 repo stars
22. ▌
    Sf AI Agentforce 5 · tools-only bundle

    Standard Agentforce platform skill. Covers Setup UI-based agent building, topic/action configuration, PromptTemplate metadata, Einstein Models API, GenAiFunction/GenAiPlugin setup, and custom Lightning types. For Agent Script DSL development, use sf-ai-agentscript instead.
    7 repo stars
23. ▌
    Write Vfunc As YAML 6 · tools-only bundle

    Write virtual function analysis results as YAML file beside the binary using IDA Pro MCP. Use this skill after completing virtual function identification, signature generation, and vtable analysis to persist the results in a standardized YAML format.
    7 repo stars
24. ▌
    Azure Diagrams 5 · tools-only bundle

    Comprehensive technical diagramming toolkit for solutions architects, presales, and developers. Creates Azure architecture diagrams (700+ official Microsoft icons), business process flows, ERD diagrams, project timelines, UI wireframes, and network topology diagrams. Also generates diagrams from Bicep, Terraform, and ARM templates. **Output format**: PNG images via Python diagrams library (mingrammer/diagrams).
    7 repo stars
25. ▌
    Find Cbasetrigger Starttouch And Cbasetrigger Endtouch 3 · tools-only bundle

    Find and identify CBaseTrigger_StartTouch and CBaseTrigger_EndTouch virtual functions in CS2 binary using IDA Pro MCP. Use this skill when reverse engineering CS2 server.dll or server.so to locate the CBaseTrigger touch handler functions by using vtable information and inherited vtable indices from CBaseEntity.
    7 repo stars
26. ▌
    Write Vtable As YAML 2 · tools-only bundle

    Write vtable analysis results as YAML file beside the binary using IDA Pro MCP. Use this skill after locating a vtable to persist the results in a standardized YAML format.
    7 repo stars
27. ▌
    Tactical Ddd 2 · tools-only bundle

    Design, refactor, analyze, and review code by applying the principles and patterns of tactical domain-driven design. Triggers on: domain modeling, aggregate design, 'entity', 'value object', 'repository', 'bounded context', 'domain event', 'domain service', code touching domain/ directories, rich domain model discussions.
    7 repo stars
28. ▌
    Citation Management 2 · tools-only bundle

    Comprehensive citation management for academic research. Search Google Scholar and PubMed for papers, extract accurate metadata, validate citations, and generate properly formatted BibTeX entries. This skill should be used when you need to find papers, verify citation information, convert DOIs to BibTeX, or ensure reference accuracy in scientific writing.
    7 repo stars
29. ▌
    Research Grants 2 · tools-only bundle

    Write competitive research proposals for NSF, NIH, DOE, DARPA, and Taiwan NSTC. Agency-specific formatting, review criteria, budget preparation, broader impacts, significance statements, innovation narratives, and compliance with submission requirements.
    7 repo stars
30. ▌
    Literature Review 2 · tools-only bundle

    Conduct comprehensive, systematic literature reviews using multiple academic databases (PubMed, arXiv, bioRxiv, Semantic Scholar, etc.). This skill should be used when conducting systematic literature reviews, meta-analyses, research synthesis, or comprehensive literature searches across biomedical, scientific, and technical domains. Creates professionally formatted markdown documents and PDFs with verified citations in multiple citation styles (APA, Nature, Vancouver, etc.).
    7 repo stars
31. ▌
    Peer Review 3 · tools-only bundle

    Structured manuscript/grant review with checklist-based evaluation. Use when writing formal peer reviews with specific criteria methodology assessment, statistical validity, reporting standards compliance (CONSORT/STROBE), and constructive feedback. Best for actual review writing, manuscript revision. For evaluating claims/evidence quality use scientific-critical-thinking; for quantitative scoring frameworks use scholar-evaluation.
    7 repo stars
32. ▌
    Latex Posters 2 · tools-only bundle

    Create professional research posters in LaTeX using beamerposter, tikzposter, or baposter. Support for conference presentations, academic posters, and scientific communication. Includes layout design, color schemes, multi-column formats, figure integration, and poster-specific best practices for visual communication.
    7 repo stars
33. ▌
    Lint 2 · tools-only bundle

    Run the plugin validator on a skill, agent, or plugin directory rts token complexity, broken links, frontmatter issues, and structural problems. Use when checking skill quality, validating before commit, or diagnosing validator warnings. Pass the path as an argument.
    7 repo stars
34. ▌
    Langchain4j MCP Server Patterns 2 · tools-only bundle

    Provides Model Context Protocol (MCP) server implementation patterns with LangChain4j. Use when building MCP servers to extend AI capabilities with custom tools, resources, and prompt templates.
    7 repo stars
35. ▌
    Spring AI MCP Server Patterns 2 · tools-only bundle

    Provides Model Context Protocol (MCP) server implementation patterns with Spring AI. Use when building MCP servers to extend AI capabilities with custom tools, resources, and prompt templates using Spring's official AI framework.
    7 repo stars
36. ▌
    Knowledge Explorer 4 · tools-only bundle

    Manage the research/ knowledge base (KB) of tool and library research entries. Use when browsing KB topics, adding new research entries, updating existing entries with dated revisions, fetching GitHub repo metadata into a draft KB entry, or migrating old-format entries to skill-spec frontmatter. Triggers on tasks like "what do we have on X", "add this to the KB", "update the KB entry for Y", "fetch github info for owner/repo", or "migrate old entries".
    7 repo stars
37. ▌
    Brainstorm Solutions 2 · tools-only bundle

    Generate multiple viable solution options after research is complete, before converging on a single approach. Use when you need to explore the solution space, ask clarifying questions, and produce 3-5 distinct options to consider.
    7 repo stars
38. ▌
    Azure Adr 4 · tools-only bundle

    Creates Azure Architecture Decision Records (ADRs) with WAF mapping, alternatives, consequences, and implementation guidance; use for architecture decision documentation requests.
    7 repo stars
39. ▌
    Bio Workflows Outbreak Pipeline 2 · tools-only bundle

    End-to-end outbreak investigation from pathogen isolates to transmission networks. Orchestrates MLST typing, AMR surveillance, phylodynamic dating, and transmission inference with TransPhylo. Use when investigating disease outbreaks or tracking pathogen transmission chains.
    7 repo stars
40. ▌
    Bio Spatial Transcriptomics Spatial Statistics 2 · tools-only bundle

    Compute spatial statistics for spatial transcriptomics data using Squidpy. Calculate Moran's I, Geary's C, spatial autocorrelation, co-occurrence analysis, and neighborhood enrichment. Use when computing spatial autocorrelation or co-occurrence statistics.
    7 repo stars
41. ▌
    Bio Comparative Genomics Synteny Analysis 2 · tools-only bundle

    Analyze genome collinearity and syntenic blocks using MCScanX, SyRI, and JCVI for comparative genomics. Detect conserved gene order, chromosomal rearrangements, and whole-genome duplications. Use when comparing genome structure between species or identifying conserved genomic regions.
    7 repo stars
42. ▌
    Bio Temporal Genomics Temporal Grn 2 · tools-only bundle

    Infers dynamic gene regulatory networks from bulk time-series expression data using Granger causality (statsmodels), dynGENIE3 (Extra-Trees on ODE-derived expression derivatives), and dynamic Bayesian networks (bnlearn). Identifies time-delayed regulatory relationships and tracks network rewiring across conditions. Use when inferring causal regulatory relationships from bulk temporal expression data or detecting TF influence propagation over time. Not for static co-expression networks (see gene-regulatory-networks/coexpression-networks).
    7 repo stars
43. ▌
    Bio Imaging Mass Cytometry Spatial Analysis 2 · tools-only bundle

    Spatial analysis of cell neighborhoods and interactions in IMC data. Covers neighbor graphs, spatial statistics, and interaction testing. Use when analyzing spatial relationships between cell types, testing for neighborhood enrichment, or identifying cell-cell interaction patterns in imaging mass cytometry data.
    7 repo stars
44. ▌
    Bio Single Cell Markers Annotation 2 · tools-only bundle

    Find marker genes and annotate cell types in single-cell RNA-seq using Seurat (R) and Scanpy (Python). Use for differential expression between clusters, identifying cluster-specific markers, scoring gene sets, and assigning cell type labels. Use when finding marker genes and annotating clusters.
    7 repo stars
45. ▌
    Bio Small Rna Seq Mirge3 Analysis 2 · tools-only bundle

    Fast miRNA quantification with isomiR detection and A-to-I editing analysis using miRge3. Use when quantifying known miRNAs quickly or analyzing isomiR variants and RNA editing.
    7 repo stars
46. ▌
    Golf Data 2 · tools-only bundle

    PGA Tour, LPGA, and DP World Tour golf data via ESPN public endpoints — tournament leaderboards, scorecards, season schedules, golfer profiles/overviews, and news. Zero config, no API keys. Use when: user asks about golf scores, tournament leaderboards, scorecards, PGA Tour schedule, golfer profiles, golfer season stats, LPGA results, or golf news. Don't use when: user asks about other sports — use football-data (soccer), nfl-data (NFL), nba-data (NBA), wnba-data (WNBA), nhl-data (NHL), mlb-data (MLB), tennis-data (tennis), cfb-data (college football), cbb-data (college basketball), or fastf1 (F1). For betting odds use polymarket or kalshi. For news use sports-news.
    7 repo stars
47. ▌
    Bio Phasing Imputation Imputation Qc 2 · tools-only bundle

    Quality control of phasing and imputation results. Filter by INFO scores, assess accuracy, and prepare imputed data for downstream analysis. Use when filtering low-quality imputed variants or validating imputation accuracy before GWAS.
    7 repo stars
48. ▌
    Bio Population Genetics Population Structure 2 · tools-only bundle

    Analyze population structure using PCA and admixture analysis with PLINK and ADMIXTURE. Identify population clusters, assess ancestry proportions, visualize genetic structure, and choose optimal K for admixture models. Use when analyzing population stratification with PCA or admixture.
    7 repo stars
49. ▌
    Bio Phylo Tree Visualization 2 · tools-only bundle

    Draw and export phylogenetic trees using Biopython Bio.Phylo with matplotlib. Use when creating publication-quality tree figures, customizing colors and labels, or exporting to image formats.
    7 repo stars
50. ▌
    Bio Transcription Translation 2 · tools-only bundle

    Transcribe DNA to RNA and translate to protein using Biopython. Use when converting between DNA, RNA, and protein sequences, finding ORFs, or using alternative codon tables.
    7 repo stars
51. ▌
    Bio Uniprot Access 2 · tools-only bundle

    Access UniProt protein database for sequences, annotations, and functional information. Use when retrieving protein data, GO terms, domain annotations, or protein-protein interactions.
    7 repo stars
52. ▌
    Holistic Linting 2 · tools-only bundle

    Comprehensive linting and formatting verification workflows. Provides automatic format-lint-resolve pipelines for orchestrators and sub-agents. Use when running linters, fixing ruff/mypy/bandit errors, ensuring code quality before completion, or resolving linting issues systematically.
    7 repo stars
53. ▌
    Agent Creator 5 · tools-only bundle

    Create high-quality Claude Code agents from scratch or by adapting existing agents as templates. Use when the user wants to create a new agent, modify agent configurations, build specialized subagents, or design agent architectures. Guides through requirements gathering, template selection, and agent file generation following January 2026 Anthropic best practices.
    7 repo stars
54. ▌
    Docs Scout 2 · tools-only bundle

    Find the most relevant framework/library docs for the requested change.
    7 repo stars
55. ▌
    Travel 2 · tools-only bundle

    Complete AI-powered travel planner with real-time weather, budget...
    7 repo stars
56. ▌
    Report Aggregator 3 · tools-only bundle

    Aggregates per-file analysis results and generates review-inline.txt and review-metadata.json
    7 repo stars
57. ▌
    Currency 2 · tools-only bundle

    Real-time currency conversion with exchange rates, historical trends, and budget calculations for travelers
    7 repo stars
58. ▌
    Progress 2 · tools-only bundle

    Create visual progress updates - charts, before/after comparisons, metrics over time
    7 repo stars
59. ▌
    Review Verification Protocol 7 · tools-only bundle

    Mandatory verification steps for all code reviews to reduce false positives. Load this skill before reporting ANY code review findings.
    7 repo stars
60. ▌
    Elixir Code Review 2 · tools-only bundle

    Reviews Elixir code for idiomatic patterns, OTP basics, and documentation. Use when reviewing .ex/.exs files, checking pattern matching, GenServer usage, or module documentation.
    7 repo stars
61. ▌
    Find Ccsplayer Movementservices Checkjumpbutton Waterpat 2 · tools-only bundle

    Find and patch the water jump velocity inside CCSPlayer_MovementServices_CheckJumpButton in CS2 binary using IDA Pro MCP. This patch changes the water jump velocity from 100.0f to 145.0f by modifying the immediate operand of a mov instruction. Use this skill when reverse engineering CS2 server.dll or server.so to locate and patch the water jump height value. Trigger: water jump patch, CheckJumpButton water velocity, jump height patch, water jump 145
    7 repo stars
62. ▌
    Find Firebullets And Traceattack And Ctakedamageinfo 5 · tools-only bundle

    Find and identify the TraceAttack function and CTakeDamageInfo struct in CS2 binary using IDA Pro MCP. Use this skill when reverse engineering CS2 server.dll or libserver.so to locate the TraceAttack function by searching for the "FireBullets" debug string pattern, then tracing through FireBullets to find TraceAttack, and identifying CTakeDamageInfo struct member offsets.
    7 repo stars
63. ▌
    Security Audit 4 · tools-only bundle

    Perform a security audit of code changes or related code paths. Use when asked to assess security risks in a PR/MR, issue, or feature area and report findings with severity and remediation.
    7 repo stars
64. ▌
    Sf Soql 4 · tools-only bundle

    Advanced SOQL skill with natural language to query generation, query optimization, relationship traversal, aggregate functions, and performance analysis. Build efficient queries that respect governor limits and security requirements.
    7 repo stars
65. ▌
    Find Ctriggerpush Touch 4 · tools-only bundle

    Find and identify the CTriggerPush_Touch (CTriggerPush::Touch) virtual function in CS2 binary using IDA Pro MCP. Use this skill when reverse engineering CS2 server.dll or server.so to locate the CTriggerPush touch handler function by using vtable information and the inherited vtable index from CBaseEntity::Touch.
    7 repo stars
66. ▌
    Bio Causal Genomics Pleiotropy Detection 2 · tools-only bundle

    Detect and correct for horizontal pleiotropy in Mendelian randomization analyses using MR-PRESSO for outlier removal, MR-Egger regression for directional pleiotropy, and Steiger filtering for variant directionality. Use when validating MR results, detecting pleiotropic instruments, or running sensitivity analyses for causal inference.
    7 repo stars
67. ▌
    Find Cbaseentity Takedamageold 4 · tools-only bundle

    Find and identify the CBaseEntity_TakeDamageOld function in CS2 binary using IDA Pro MCP. Use this skill when reverse engineering CS2 server.dll or libserver.so to locate the TakeDamageOld function by searching for the TakeDamageOld debug string references and analyzing cross-references.
    7 repo stars
68. ▌
    Sf Data 3 · tools-only bundle

    Salesforce data operations expert with 130-point scoring. Use when writing SOQL queries, creating test data, performing bulk data operations, or importing/exporting data via sf CLI.
    7 repo stars
69. ▌
    Find Igamesystem Looppostinitallsystems Peventdispatcher 3 · tools-only bundle

    Find and identify the IGameSystem_LoopPostInitAllSystems_pEventDispatcher and IGameSystem_LoopDestroyAllSystems_s_GameSystems global variable in CS2 binary using IDA Pro MCP. Use this skill when reverse engineering CS2 server.dll or libserver.so to locate the event dispatcher pointer by searching for the "IGameSystem::LoopPostInitAllSystems(finish)" string reference and analyzing cross-references.
    7 repo stars
70. ▌
    Airflow 5 · tools-only bundle

    Manages Apache Airflow operations including listing, testing, running, and debugging DAGs, viewing task logs, checking connections and variables, and monitoring system health. Use when working with Airflow DAGs, pipelines, workflows, or tasks, or when the user mentions testing dags, running pipelines, debugging workflows, dag failures, task errors, dag status, pipeline status, list dags, show connections, check variables, or airflow health.
    7 repo stars
71. ▌
    Bio Longitudinal Monitoring 2 · tools-only bundle

    Tracks ctDNA dynamics over time for treatment response monitoring using serial liquid biopsy samples. Analyzes tumor fraction trends, mutation clearance kinetics, and defines molecular response criteria. Use when monitoring patients during therapy or detecting molecular relapse before clinical progression.
    7 repo stars
72. ▌
    Bio Clinical Databases Hla Typing 2 · tools-only bundle

    Call HLA alleles from NGS data using OptiType, HLA-HD, or arcasHLA for immunogenomics applications. Use when determining HLA genotype for transplant matching, neoantigen prediction, or pharmacogenomic screening.
    7 repo stars
73. ▌
    Bio Temporal Genomics Trajectory Modeling 2 · tools-only bundle

    Models continuous temporal trajectories from bulk or time-resolved omics data using generalized additive models (mgcv), spline regression, and changepoint detection (segmented, ruptures). Fits smooth gene expression curves and tests trajectory differences between conditions. Use when fitting non-linear temporal models to bulk time-series data or comparing developmental trajectories across conditions. Not for single-cell pseudotime (see single-cell/trajectory-inference).
    7 repo stars
74. ▌
    Bio Ecological Genomics Biodiversity Metrics 2 · tools-only bundle

    Calculates species richness, diversity, and turnover using the Hill number framework with iNEXT coverage-based rarefaction/extrapolation, asymptotic diversity estimation, and beta diversity partitioning (betapart turnover vs nestedness). Compares assemblages using coverage-standardized rather than size-standardized rarefaction. Use when quantifying biodiversity from species abundance or incidence data, comparing diversity across sites, or constructing rarefaction curves. Not for clinical 16S microbiome alpha/beta diversity (see microbiome/diversity-analysis).
    7 repo stars
75. ▌
    Bio Data Visualization Color Palettes 2 · tools-only bundle

    Select and apply colorblind-friendly palettes for scientific figures using viridis, RColorBrewer, and custom color schemes. Use when selecting colorblind-friendly palettes for figures.
    7 repo stars
76. ▌
    Bio Microbiome Diversity Analysis 3 · tools-only bundle

    Alpha and beta diversity analysis for microbiome data. Calculate within-sample richness, evenness, and between-sample dissimilarity with phyloseq and vegan. Use when comparing community composition across samples or testing for group differences in microbiome structure.
    7 repo stars
77. ▌
    Bio Differential Expression Timeseries De 3 · tools-only bundle

    Analyze time-series RNA-seq data using limma voom with splines, maSigPro, and ImpulseDE2. Identify genes with dynamic expression patterns. Use when analyzing time-series or longitudinal expression data.
    7 repo stars
78. ▌
    Bio Sra Data 2 · tools-only bundle

    Download sequencing data from NCBI SRA using the SRA toolkit. Use when downloading FASTQ files from SRA accessions, prefetching large datasets, or validating SRA downloads.
    7 repo stars
79. ▌
    Bio Tcr Bcr Analysis Mixcr Analysis 2 · tools-only bundle

    Perform V(D)J alignment and clonotype assembly from TCR-seq or BCR-seq data using MiXCR. Use when processing raw immune repertoire sequencing data to identify clonotypes and their frequencies.
    7 repo stars
80. ▌
    Bio Gene Regulatory Networks Perturbation Simulation 2 · tools-only bundle

    Simulate transcription factor perturbation effects on cell state using CellOracle, which integrates GRN inference with in silico knockout and overexpression modeling. Predicts cell identity shifts and differentiation trajectory changes from TF perturbations. Use when predicting the effect of transcription factor knockouts, planning perturbation experiments, or identifying driver TFs for cell fate transitions.
    7 repo stars
81. ▌
    Bio Genome Annotation Functional Annotation 2 · tools-only bundle

    Assign GO terms, KEGG orthologs, Pfam domains, and EC numbers to predicted proteins using eggNOG-mapper and InterProScan. Produces functional summaries for downstream pathway and enrichment analysis. Use when adding functional annotation to predicted genes or characterizing protein functions in a new genome.
    7 repo stars
82. ▌
    Triage 2 · tools-only bundle

    Strategically route orphaned files and extract scattered tasks
    7 repo stars
83. ▌
    Bio Seq Objects 2 · tools-only bundle

    Create and manipulate Seq, MutableSeq, and SeqRecord objects using Biopython. Use when creating sequences from strings, modifying sequence data in-place, or building annotated sequence records.
    7 repo stars
84. ▌
    Vite Flare Starter 2 · tools-only bundle

    Scaffold a full-stack Cloudflare app from vite-flare-starter — React 19, Hono, D1+Drizzle, better-auth, Tailwind v4+shadcn/ui, TanStack Query, R2, Workers AI. Run setup.sh to clone, configure, and deploy.
    7 repo stars
85. ▌
    Generate Signature For Structoffset 2 · tools-only bundle

    Generate and validate unique byte signatures for instructions containing a struct member offset using IDA Pro MCP. Use this skill when you need a signature for an instruction like mov [rcx+1A8h], eax or cmp dword ptr [rdi+0B0h], 0, where the struct offset must be explicitly fixed in the first instruction bytes. Triggers: struct offset signature, signature for struct offset, structure member offset signature, mov [reg+offset] signature, struct field signature
    7 repo stars
86. ▌
    Board Of Directors 2 · tools-only bundle

    Simulate a 5-member expert board deliberation for major decisions. Use when evaluating plans, architecture choices, feature designs, or any decision requiring multi-perspective expert analysis. Triggers: 'board review', 'get expert opinions', 'board meeting', 'director evaluation', 'consensus review'.
    7 repo stars
87. ▌
    Azure Diagrams 6 · tools-only bundle

    Generates Azure and technical architecture diagrams (PNG via Python diagrams) from requirements or IaC, including topology, process flow, ERD, and wireframe visuals.
    7 repo stars
88. ▌
    Find Cbaseentity Starttouch And Cbaseentity Touch Cbasee 2 · tools-only bundle

    Find and identify the CBaseEntity_StartTouch, CBaseEntity_Touch, and CBaseEntity_EndTouch virtual functions in CS2 binary using IDA Pro MCP. Use this skill when reverse engineering CS2 server.dll or server.so to locate these touch-related virtual functions by searching for the "INVALID CGameEventStartTouchCollideAdaptor" string reference and analyzing the touch event handler functions.
    7 repo stars
89. ▌
    Sf AI Agentforce 6 · tools-only bundle

    Standard Agentforce platform skill. Covers Setup UI-based agent building, topic/action configuration, PromptTemplate metadata, Einstein Models API, GenAiFunction/GenAiPlugin setup, and custom Lightning types. For Agent Script DSL development, use sf-ai-agentscript instead.
    7 repo stars
90. ▌
    Gemini Guide 2 · tools-only bundle

    Look up Gemini API documentation, SDK patterns, and current best practices when building with Google Gemini. Maps topics to local cached docs and live sources, provides correct @google/genai patterns, and highlights deprecated vs current API usage. Trigger with 'gemini docs', 'gemini guide', 'how to use gemini', 'gemini SDK', '@google/genai', or when building code that imports from @google/genai or google-genai.
    7 repo stars
91. ▌
    Bio Read Sequences 2 · tools-only bundle

    Read biological sequence files (FASTA, FASTQ, GenBank, EMBL, ABI, SFF) using Biopython Bio.SeqIO. Use when parsing sequence files, iterating multi-sequence files, random access to large files, or high-performance parsing.
    7 repo stars
92. ▌
    Gh 2 · tools-only bundle

    Install and configure the GitHub CLI (gh) for AI agent environments where gh may not be pre-installed and git remotes use local proxies instead of github.com. Provides auto-install script with SHA256 verification and GITHUB_TOKEN auth with anonymous fallback. Use when gh command not found, shutil.which("gh") returns None, need GitHub API access (issues, PRs, releases, workflow runs), or repository operations fail with "failed to determine base repo" error. Documents required -R flag for all gh commands in proxy environments. Includes project management: GitHub Projects V2 (gh project), milestones (REST API), issue stories (lifecycle and templates), and label taxonomy management.
    7 repo stars
93. ▌
    Git Commit 4 · tools-only bundle

    Execute git commit with conventional commit message analysis, intelligent staging, and message generation. Use when user asks to commit changes, create a git commit, or mentions "/commit". Supports: (1) Auto-detecting type and scope from changes, (2) Generating conventional commit messages from diff, (3) Interactive commit with optional type/scope/description overrides, (4) Intelligent file staging for logical grouping
    7 repo stars
94. ▌
    Review Verification Protocol 11 · tools-only bundle

    Mandatory verification steps for all code reviews to reduce false positives. Load this skill before reporting ANY code review findings.
    7 repo stars
95. ▌
    Plan Sync 2 · tools-only bundle

    Synchronizes downstream task specs after implementation. Spawned by flow-next-work after each task completes. Do not invoke directly.
    7 repo stars
96. ▌
    Langchain4j AI Services Patterns 2 · tools-only bundle

    Build declarative AI Services with LangChain4j using interface-based patterns, annotations, memory management, tools integration, and advanced application patterns. Use when implementing type-safe AI-powered features with minimal boilerplate code in Java applications.
    7 repo stars
97. ▌
    Fecfile 2 · tools-only bundle

    Analyze FEC (Federal Election Commission) campaign finance filings. Use when working with FEC filing IDs, campaign finance data, contributions, disbursements, or political committee financial reports.
    7 repo stars
98. ▌
    Monitoring Whale Activity 2 · tools-only bundle

    Track large cryptocurrency transactions and whale wallet movements in real-time. Use when tracking large holder movements, exchange flows, or wallet activity. Trigger with phrases like "track whales", "monitor large transfers", "check whale activity", "exchange inflows", or "watch wallet".
    7 repo stars
99. ▌
    Canslim Screener 3 · tools-only bundle

    Screen US stocks using William O'Neil's CANSLIM growth stock methodology. Use when user requests CANSLIM stock screening, growth stock analysis, momentum stock identification, or wants to find stocks with strong earnings and price momentum following O'Neil's investment system.
    7 repo stars
100. ▌
     Breadth Chart Analyst 2 · tools-only bundle

     This skill should be used when analyzing market breadth charts, specifically the S&P 500 Breadth Index (200-Day MA based) and the US Stock Market Uptrend Stock Ratio charts. Use this skill when the user provides breadth chart images for analysis, requests market breadth assessment, positioning strategy recommendations, or wants to understand medium-term strategic and short-term tactical market outlook based on breadth indicators. All analysis and output are conducted in English.
     7 repo stars